Parkinsonism with HIV infection.
Identifieur interne : 003852 ( Main/Exploration ); précédent : 003851; suivant : 003853Parkinsonism with HIV infection.
Auteurs : S M Mirsattari [Canada] ; C. Power ; A. NathSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 1998.
English descriptors
- KwdEn :
- AIDS Dementia Complex (diagnosis), AIDS Dementia Complex (drug therapy), AIDS-Related Opportunistic Infections (diagnosis), AIDS-Related Opportunistic Infections (drug therapy), Adult, Anti-HIV Agents (adverse effects), Anti-HIV Agents (therapeutic use), Antipsychotic Agents (adverse effects), Benztropine (adverse effects), Benztropine (therapeutic use), Drug Therapy, Combination, HIV Infections (diagnosis), HIV Infections (drug therapy), Homosexuality, Male, Humans, Male, Neurologic Examination (drug effects), Parkinson Disease, Secondary (chemically induced), Parkinson Disease, Secondary (diagnosis), Risk Factors, Zidovudine (adverse effects), Zidovudine (therapeutic use).
- MESH :
- chemical , adverse effects : Anti-HIV Agents, Antipsychotic Agents, Benztropine, Zidovudine.
- chemically induced : Parkinson Disease, Secondary.
- diagnosis : AIDS Dementia Complex, AIDS-Related Opportunistic Infections, HIV Infections, Parkinson Disease, Secondary.
- drug effects : Neurologic Examination.
- drug therapy : AIDS Dementia Complex, AIDS-Related Opportunistic Infections, HIV Infections.
- chemical , therapeutic use : Anti-HIV Agents, Benztropine, Zidovudine.
- Adult, Drug Therapy, Combination, Homosexuality, Male, Humans, Male, Risk Factors.
Abstract
We describe six patients with parkinsonism and another 10 patients with parkinsonian features with human immunodeficiency virus (HIV) infection. In 50% of these patients, the symptoms were precipitated by neuroleptics. In the remaining patients, no obvious cause other than HIV infection was identified. Discontinuation of the neuroleptics produced complete recovery in one patient and partial or no response in others. Rapid progression of parkinsonism was noted in two patients, one of whom was treated with high-dose zidovudine (AZT) and benztropine. We conclude that patients with AIDS are at risk of developing an akinetic parkinsonism which may be precipitated by the use of neuroleptics, response to treatment is variable, and parkinsonism may be another primary HIV-induced syndrome.
DOI: 10.1002/mds.870130413
PubMed: 9686775
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 001761
- to stream PubMed, to step Curation: 001761
- to stream PubMed, to step Checkpoint: 001761
- to stream Ncbi, to step Merge: 002653
- to stream Ncbi, to step Curation: 002653
- to stream Ncbi, to step Checkpoint: 002653
- to stream Main, to step Merge: 003E45
- to stream Main, to step Curation: 003852
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Parkinsonism with HIV infection.</title><author><name sortKey="Mirsattari, S M" sort="Mirsattari, S M" uniqKey="Mirsattari S" first="S M" last="Mirsattari">S M Mirsattari</name><affiliation wicri:level="4"><nlm:affiliation>Department of Internal Medicine, University of Manitoba, Winnipeg, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Internal Medicine, University of Manitoba, Winnipeg</wicri:regionArea><orgName type="university">Université du Manitoba</orgName><placeName><settlement type="city">Winnipeg</settlement><region type="state">Manitoba</region></placeName></affiliation></author><author><name sortKey="Power, C" sort="Power, C" uniqKey="Power C" first="C" last="Power">C. Power</name></author><author><name sortKey="Nath, A" sort="Nath, A" uniqKey="Nath A" first="A" last="Nath">A. Nath</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1998">1998</date><idno type="RBID">pubmed:9686775</idno><idno type="pmid">9686775</idno><idno type="doi">10.1002/mds.870130413</idno><idno type="wicri:Area/PubMed/Corpus">001761</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001761</idno><idno type="wicri:Area/PubMed/Curation">001761</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001761</idno><idno type="wicri:Area/PubMed/Checkpoint">001761</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001761</idno><idno type="wicri:Area/Ncbi/Merge">002653</idno><idno type="wicri:Area/Ncbi/Curation">002653</idno><idno type="wicri:Area/Ncbi/Checkpoint">002653</idno><idno type="wicri:doubleKey">0885-3185:1998:Mirsattari S:parkinsonism:with:hiv</idno><idno type="wicri:Area/Main/Merge">003E45</idno><idno type="wicri:Area/Main/Curation">003852</idno><idno type="wicri:Area/Main/Exploration">003852</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Parkinsonism with HIV infection.</title><author><name sortKey="Mirsattari, S M" sort="Mirsattari, S M" uniqKey="Mirsattari S" first="S M" last="Mirsattari">S M Mirsattari</name><affiliation wicri:level="4"><nlm:affiliation>Department of Internal Medicine, University of Manitoba, Winnipeg, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Internal Medicine, University of Manitoba, Winnipeg</wicri:regionArea><orgName type="university">Université du Manitoba</orgName><placeName><settlement type="city">Winnipeg</settlement><region type="state">Manitoba</region></placeName></affiliation></author><author><name sortKey="Power, C" sort="Power, C" uniqKey="Power C" first="C" last="Power">C. Power</name></author><author><name sortKey="Nath, A" sort="Nath, A" uniqKey="Nath A" first="A" last="Nath">A. Nath</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="1998" type="published">1998</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>AIDS Dementia Complex (diagnosis)</term><term>AIDS Dementia Complex (drug therapy)</term><term>AIDS-Related Opportunistic Infections (diagnosis)</term><term>AIDS-Related Opportunistic Infections (drug therapy)</term><term>Adult</term><term>Anti-HIV Agents (adverse effects)</term><term>Anti-HIV Agents (therapeutic use)</term><term>Antipsychotic Agents (adverse effects)</term><term>Benztropine (adverse effects)</term><term>Benztropine (therapeutic use)</term><term>Drug Therapy, Combination</term><term>HIV Infections (diagnosis)</term><term>HIV Infections (drug therapy)</term><term>Homosexuality, Male</term><term>Humans</term><term>Male</term><term>Neurologic Examination (drug effects)</term><term>Parkinson Disease, Secondary (chemically induced)</term><term>Parkinson Disease, Secondary (diagnosis)</term><term>Risk Factors</term><term>Zidovudine (adverse effects)</term><term>Zidovudine (therapeutic use)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Anti-HIV Agents</term><term>Antipsychotic Agents</term><term>Benztropine</term><term>Zidovudine</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Parkinson Disease, Secondary</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>AIDS Dementia Complex</term><term>AIDS-Related Opportunistic Infections</term><term>HIV Infections</term><term>Parkinson Disease, Secondary</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Neurologic Examination</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>AIDS Dementia Complex</term><term>AIDS-Related Opportunistic Infections</term><term>HIV Infections</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-HIV Agents</term><term>Benztropine</term><term>Zidovudine</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Drug Therapy, Combination</term><term>Homosexuality, Male</term><term>Humans</term><term>Male</term><term>Risk Factors</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We describe six patients with parkinsonism and another 10 patients with parkinsonian features with human immunodeficiency virus (HIV) infection. In 50% of these patients, the symptoms were precipitated by neuroleptics. In the remaining patients, no obvious cause other than HIV infection was identified. Discontinuation of the neuroleptics produced complete recovery in one patient and partial or no response in others. Rapid progression of parkinsonism was noted in two patients, one of whom was treated with high-dose zidovudine (AZT) and benztropine. We conclude that patients with AIDS are at risk of developing an akinetic parkinsonism which may be precipitated by the use of neuroleptics, response to treatment is variable, and parkinsonism may be another primary HIV-induced syndrome.</div></front></TEI><affiliations><list><country><li>Canada</li></country><region><li>Manitoba</li></region><settlement><li>Winnipeg</li></settlement><orgName><li>Université du Manitoba</li></orgName></list><tree><noCountry><name sortKey="Nath, A" sort="Nath, A" uniqKey="Nath A" first="A" last="Nath">A. Nath</name><name sortKey="Power, C" sort="Power, C" uniqKey="Power C" first="C" last="Power">C. Power</name></noCountry><country name="Canada"><region name="Manitoba"><name sortKey="Mirsattari, S M" sort="Mirsattari, S M" uniqKey="Mirsattari S" first="S M" last="Mirsattari">S M Mirsattari</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003852 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003852 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Canada
|area= ParkinsonCanadaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:9686775
|texte= Parkinsonism with HIV infection.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:9686775" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a ParkinsonCanadaV1
| This area was generated with Dilib version V0.6.29. |  |